UNC faculty gets Nobel Prize for DNA repair mechanisms!!

Dr. Aziz Sancar, just won the Nobel Prize for chemistry today, along with two other scientists,Dr.Tomas Lindahl from the Francis Crick Institute and Clare Hall Laboratory, and Dr. Paul Modrich, from Duke University.  All study different mechanisms of DNA repair. The coolest thing is that my micro class just studied all three repair mechanisms. One of the things Dr. Sancar stated in the news conference at UNC, that an understanding of how DNA gets mutated, and how the cell fixes these mutations, is integral in understanding the foundations of cancer, as well as the establishing an understanding of a treatment for cancer.

Dr. Sancar studies the mechanism behind UV (sunlight damage) called thymine dimer repair, called excision repair (link to Youtube animation).

Dr. Modrich studies the mechanism behind mismatch repair (link to Youtube animation)

Dr. Lindahl studies the mechanisms of repair behind oxidative damage, called base excision repair.

Dr. Aziz Sancar discussing his Nobel Prize in Chemistry at UNC Marsico Hall

Dr. Aziz Sancar discussing his Nobel Prize in Chemistry at UNC Marsico Hall

 

About Dr. Cramer

Dr. Lorraine Cramer teaches undergraduate Microbiology and Immunology to students at the University of North Carolina in Chapel Hill.
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